showed the significant promise of the approach on manually implemented example models, research is required to achieve a broad applicability and to systematically study the approach. Hence, the project [...] techniques. The methods are demonstrated and evaluated on optimization and calibration problems from the domains of road traffic and cell biology. Agent-based simulations are used in the design and evaluation [...] solved by iteratively adjusting the parameters of the simulation model, which is associated with immense computation times. Gradient information, which could steer the optimization process towards local
https://mosi.informatik.uni-rostock.de/en/research/projects/soda/